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The risks, which range from lowered sperm quality to disrupted endocrine function, make nicotine a poor choice for any man looking to optimize his hormones or health
doi:10.1176/appi.ps.201800321 pmid:30554562 Mello NK, Newman JL (2011) Discriminative and reinforcing stimulus effects of nicotine, cocaine, and cocaine + nicotine combinations in rhesus monkeys

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In the kidneys, these processes can damage the delicate structures responsible for filtering blood (glomeruli) and maintaining the balance of electrolytes and fluids
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Lets evaluate both devices in the review and how each vape style differs