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Although these pathways show that exposure to nicotine directly disrupts monoaminergic systems, disruptions of the endogenous cholinergic system, whether direct or indirect, remain a possibility

No matter that the beat lacked the sort of languid rhythm and ecstatic energy that trap anthems normally require, Flocka carried this on his own

the same is true for time since cessation, cumulative smoking (e.g., pack-years [which is defined as the number of packs of cigarettes smoked per day multiplied by the number of years smoked], which incorporates both smoking intensity and duration), and changes in smoking status during follow-up

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