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Several systemic drugs have been reported to help in RAS that does not respond to topical therapy

The targeted marketing of menthol cigarettes to Black individuals has contributed to about 77% of Black smokers using menthol cigarettes, compared to 23% of white smokers

These changes in the olfactory neuroepithelium (the lining of the nerves) may be structural and/or functional

Sidestream smoke puts individuals at an increased risk of bladder cancer because the 4-ABP concentrations are over ten times that of mainstream smoke