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An evaluation by the FDA determined the Zyn pouches contained substantially lower amounts of harmful ingredients than cigarettes and smokeless tobacco products while posing a lower risk of cancer and other serious health conditions than those products, according to the agency

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The study, which was published in the British Medical Journal, found that participants who had vaped within the last month were 81 percent more likely to wheeze compared to those who had never used vapes

These results were robust to various sensitivity analyses, including restricting data point inclusion based on exposure definitions and sample sizes (Fig