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This is explained not only by reduced renal clearance, but also by lower metabolic clearance of nicotine in renal disease

The decision, which does not mean the products are safe or FDA approved, indicates that the agency determined tobacco-flavored Vuse Solo has potential to benefit public health by helping smokers transition to a product that reduces their exposure to harmful ingredients

It was designed to shine a light on how, in many countries, health warnings and packaging regulations now plaguing the tobacco category can spill over to soda, energy drinks, alcohol and candy

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