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doi: 10.35198/01-2020-002-0007 [DOI] [Google Scholar] 6

But her laugh turns into a cough and she says, and that comes from smoking a cigarette. Marianne, now in her late 50s, says she started smoking when she was 11 years old

Why digress so
However the effects of nicotine in tobacco are difficult to separate from the other chemicals, tar and smoke that are in cigarettes

Polish Annals of Medicine/Rocznik Medyczny

Around 90% of the plants nicotine content is concentrated in the central vein of the leaf, thus pulling out the vein makes the cigar almost nicotine-free
