department of tobacco and alcohol Home Brewers' Law 101: Federal TTB
Description
Nicotine increases dopamine, used for motivation and focus, and thyroid hormone used for energy and lowers thyroid stimulating hormone (TSH) so researchers believe that nicotine withdrawals are actually a combination of thyroid hormone and dopamine withdrawals and not actually from the nicotine itself

I wanted to try this based on reviews

Flue-curing involves yellowing, leaf drying, and stalk drying processes that take place in a flue-curing barn
One of the refrains we hear from kids who do this kind of work is, when they get the tobacco sickness, they say, I felt like I was going to die,' said Reid Maki, Director of Social Responsibility and Fair Labor Standards Coordinator, Child Labor Coalition for National Consumers League

A tobacco pellet measures 1.0 x 0.5 cm and has a natural content of nicotine
Broadleaf is now often used to make Maduro cigars
