glp-1 pathophysiology and the kidney: from physiology to pharmacology and outcomes in diabetes GLP-1-based therapies for type 2
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doi: 10.1042/BJ20050113
46 , 47 Considerable evidence suggests that GLP-1 medicines may reduce the rewarding effects of several addictive substances in rodent models of SUD and in humans, 48 reflecting actions of GLP-1 to modulate the mesolimbic system
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In addition, in order to compare the pharmacological efficacy of the multi-agonists with the standard treatment, subgroups of animals were orally treated with a daily dose of metformin (300 mg/kg)
