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1,3,5-Tris(pyridin-3-ylethynyl)benzene is a metal-organic framework (MOF)

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Insulin resistance and cytokine production are key mechanisms leading to fatty change in the liver and may produce nonalcoholic steatohepatitis (NASH)

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Here, we provide structural evidence for the ability of the glutaminase enzymes to form filaments upon substrate binding, and present the first cryo-EM structures of the human full-length glutaminase isozyme GLS2 that offer an unprecedented view of the mechanism responsible for catalyzing glutamine hydrolysis

Based on solid values, it has stood the test of time and will continue to do so in the future with the same determination.