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Therefore, the smoking-cessation induced decrease in cortisol levels may exacerbate withdrawal symptomatology and relapse by facilitating the recovery of nAChRs
Epidemiologic studies indicate that exclusive use of Swedish snus, which contains low levels of carcinogenic tobacco-specific nitrosamines (TSNA), is associated with relatively low risk of cancer compared to other forms of smokeless tobacco

National Institute on Drug Abuse (NIDA)

It has also been estimated that approximately 14 million U.S

Villard et al., 1998), critical for metabolizing substances such as chlorzoxazone

doi:10.1136/tobaccocontrol-2019-055530 9
