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So, nicotine is not only addictive, it is also a health risk

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The genes behind this combination exist in many plants, but genetic duplications in the nightshade family are believed to have led to higher nicotine production in tobacco plants

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For some, nicotine abstinence may actually worsen symptoms of mental disorders.[10] Moreover, about 20 years ago, major tobacco US manufacturers recognized that a large proportion of their customer population was individuals with underlying psychiatric disorders