glp 1 receptor agonist natural PDB-101: Molecule of the Month: GLP-1 Agonists GLP-1 receptor agonists for individualized
Description
GLP-1 medications, like semaglutide (Ozempic, Wegovy), were originally developed to help people with type 2 diabetes manage blood sugar

A study of liraglutide identified 0.188 cases per 100 person-years (PY) versus 0.154 in patients taking MET (an SU) or pioglitazone (a TZD)

In addition, hyperandrogenism by itself stimulates the deposition of adipose tissue in the visceral area, with further increase in insulin resistance, thus contributing to the vicious circle [17]
He K, Hu H, Ye S, Wang H, Cui R, Yi L

[39,40] Semaglutide is weekly injectable and a daily oral form, has a particularly long half-life of about one week in its injectable form, permitting less frequent dosing
Patients on GLP-1 drugs tend to have EWDR for one to two years after rapid A1c improvement
