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On cigarette packs, it is usually no expiration date indicated, as tobacco has a very long minimum shelf life

Pearce J, Rind E, Shortt N, Tisch C, and Mitchell R

2024 Jayraj Tobacco

However, they also increase the levels of tumor necrosis factoralpha (TNF) in the plasma [142]

I guess this gets at why its so important for the research to identify the specific problems and the specific mechanisms, because, like, if the main way that social media is causing depression or anxiety in teens is because its preventing them from getting enough sleep and its preventing them from seeing their friends in public, just purely hypothetically, like then what you could, like, deduce from that is that, like, okay, maybe these products are just too addictive, and our kids are being sort of coerced into staying on them for too long