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Description
Brain imaging studies document a decrease in brain MAO in chronic cigarette smokers, with a roughly 3040% inhibition (Fowler et al., 2003a)

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While other studies have echoed these claims, most were funded by tobacco companies, leading some to challenge their reliability

Conclusions and clinical implications Taken together, there is strong evidence from human studies that tobacco cigarette smoke exposure has severe cardiovascular side effects leading to ED, increased oxidative stress, inflammation, and ultimately to increased cardiovascular morbidity and mortality

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For example, some provinces require online vendors to be registered or licensed to sell tobacco products within their jurisdiction
