jens juul holst glp 1 The Story of GLP-1 Jens Juul Holst – Dansk

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But are they safe for long-term use

As these drugs spread to younger and healthier people, a clinical guide tries to replace one-size-fits-all prescribing with something more honest about risk, goals, and how patients are treated.

Some of the dual and triple agonists have already shown initial successes in clinical trials, although the molecular mechanisms underlying their multiplexed pharmacology remain elusive

Further studies are needed to assess the potential cardiovascular and renal benefits of combination therapy and to determine suitable patient population for the therapy