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After repeated use, the body begins to develop a tolerance to the effects and craves more nicotine to induce the pleasurable feelings

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(A person inhaling a nicotine aerosol usually absorbs 80% of the nicotine, 48 whereas the pump discharges all nicotine into the environment, so the nicotine exposure may be higher in this study than would be the case with actual secondhand aerosol exposure.) Serum cotinine in nonsmokers sitting in the chamber was similar for cigarette smoke and e-cigarette aerosol exposure (average, 0.8 ng/mL for tobacco cigarette and 0.5 ng/mL for e-cigarette)

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Vapes can deliver nicotine by heating a liquid and turning it into a fine spray for inhalation rather than burning tobacco like regular smokes