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Note that participants in the previously published pilot study (14) are included in this manuscript due to the fact that the present analysis includes additional metabolites and comparison of all outcomes across product formulations

The UK flavour set is intentionally restrained (menthols/tobaccos + a couple of fruits), which many people find calming in week one

Packaging forms include hard packs, soft packs, and wooden boxes

The moisture in the air condenses because air can hold less moisture at low temperatures

We are limited to concluding only that our data were consistent with our hypothesized and theory-guided mediational model, and acknowledge that alternative models with different causal assumptions (e.g., bi-directional relationships) may also fit the data equally as well

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