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Abstaining from marijuana after long-term use can lead to improvements in cognitive performance, including enhanced memory, attention, and executive function, as the brain recovers from the effects of chronic use

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[3] In Russia in 1643, Tsar Michael prohibited the sale of tobacco, instituted the punishment of removing the nose of those who used snuff, and declared that persistent users of tobacco would be killed

This study identifies mutational signatures associated with smoking in human cancer