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Ashes to Ashes: America's Hundred-Year Cigarette War, the Public Health, and the Unabashed Triumph of Philip Morris (Vintage, 1997)

In cigarette smoke, it affects the bodys ability to use oxygen, which can lead to cell damage, weakened immunity, and respiratory issues

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Structural rationalization for the nonmutagenic and mutagenic bypass of the tobacco-derived O 4 -4-(3-pyridyl)-4-oxobut-1-yl-thymine lesion by human polymerase eta: a multiscale computational study