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Evidence is emerging that glucagon-like peptide-1 (GLP-1) receptor agonists have anti-inflammatory and chondroprotective properties independent of their effects on weight loss

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Most patients see measurable changes within 24 weeks, with results accelerating as doses increase over time

Strategic implications: For healthcare executives and policy leaders, this signals evolving payer conversations, updated treatment guidelines, and new opportunitiesbut also demands close attention to long-term efficacy and safety data

Results At week 4 after discontinuation, compared with the control group, AOM treatment still had weight loss effect (WMD=0.32 kg, 95% CI3.602.97, P=0.85, I2=83%)

However, there is growi...