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The same industry of which an executive was asked the question, Which brand do you smoke and answered, We dont smoke that sh-t

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Cigarette smoke-induced oxidative stress suppresses generation of dendritic cell IL-12 and IL-23 through ERK-dependent pathways

For example, smokers who use cigarettes at the rate of a pack a day elevate the level of carbon monoxide in their blood to three times the level normally present in nonsmokers, and in this respect alone smoking exacerbates any predisposition on the part of the smokers to heart and lung disease and possibly increases the danger of arteriosclerosis