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Abstract Glucagon-like peptide-1 (GLP-1) receptor is widely distributed in the digestive system, cardiovascular system, adipose tissue and central nervous system
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Specifically, 0.2% of patients in the GLP-1 RA group developed nAMD, compared with 0.1% in the unexposed group
In 2006 weekly and biweekly antibody-based therapies, such as the TNF (tumour necrosis factor)-inhibitors Humira (adalimumab from Abbott, now AbbVie) and Enbrel (etanercept from Amgen and Pfizer), were introduced for the treatment of rheumatoid arthritis
The ability of GLP-1s to potentially stave off the progression to other chronic diseases represents a paradigm shift in preventative medicine
