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Description
The oesophagus and stomach lining are destroyed by frequent occurrences of acid reflux

Several early studies of large numbers of persons with the PI *Z allele demonstrated that PI *Z- type persons who smoked cigarettes tended to develop more severe COPD at an earlier age than did PI *Z- type persons who were nonsmokers (Larsson 1978

[PubMed: 6475921] Li XY, Donaldson K, Rahman I, MacNee W

Tobacco farmers often experience this disease

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Magazine were mainstays of cigarette advertising
