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A 2024 systematic review found some positive results (66.7% of studies reported positive impact), but methodological issues in those studies (small sample sizes, lack of biochemical validation, poor randomization) make it hard to draw firm conclusions

In addition, lesions to the anterior cingulate cortex (ACC) have been shown to increase fear response to a conditioned stimulus [82]

Cell Cycle 9:389397 Mantovani A (2010) Molecular pathways linking inflammation and cancer

Primary syphilis usually presents itself as a single sore

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