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doi: 10.1152/ajplung.00452.2016

These products are highly flammable, so you should never use them while smoking

More than 20 studies, undertaken over two decades in five countries, strongly suggest that plain packaging increases the impact of health warnings and reduces the appeal of cigarettes

Further experiments revealed that the nicotine-NLRP3-ASC-pyroptosis pathway was activated by reactive oxygen species (ROS), since ROS scavenger (N-acetyl-cysteine, NAC) prevented endothelial cell pyroptosis

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