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Interestingly, however, 6/32 cases (18%) of PanIN were GLP1R positive by immunohistochemistry (Table 1)

For instance, a study published in 2022 indicated that semaglutide could reduce levels of C-reactive protein, a marker of inflammation, suggesting a potential protective effect against inflammation-related conditions

To minimise side effects and allow the body to acclimatise to the medication, it is recommended to start semaglutide at a low dose of 0.25mg or 0.5mg per week for 1 month, before increasing to a medium dose of 1mg per week

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