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Over time, this can lead to chronic bronchitis, asthma-like symptoms, and permanent lung damage
Washington, DC: National Academies Press (US) (2018)
Furthermore, since metabolism of varenicline represents less than 10% of its clearance, drugs known to affect the cytochrome P450 system are unlikely to alter the pharmacokinetics of CHANTIX [see Clinical Pharmacology (12.3)]
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