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FIGURE 1 Smoke exposure increases the number of lung dendritic cells (DCs), which may reduce the number of myeloid DCs migrating to the lymph nodes ( Salmonella via upregulating the gut-homing integrin 47 and inducing T-cell migration to the intestinal tract ( Interleukin-6 (IL-6) exerts a pivotal role in regulating many cellular process and has been implicated in the pathogenesis of various inflammatory disorders such as COPD and IBD ( trans- signaling, which results in T-cell resistance to apoptosis by inducing the expression of the anti-apoptotic factors bcl-2 and bcl-xl

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Clin Chim Acta 426:5157

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