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This may contribute the COPD pathology, inducing apoptosis, tissue damage as well as airway inflammation, since airway epithelial cells respond to increased ROS levels by producing cytokines/chemokines that attract inflammatory cells to the area of damage [5, 6, 21, 23, 24]

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The bill would also (1) grant the state board of health authority to determine the allowable nicotine concentration for vapor products sold in the state, and (2) establish a rule that manufacturers must disclose the products nicotine form and concentration, including all ingredients or product elements that may be inhaled when used