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Using a statistical approach known as mediation analysis, the researchers determined the sequence of events: genetic predisposition leads to smoking, which leads to decreased brain volume

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Effects of diet, exercise, stress, and other variables

Here was a less harmful alternative to cigarettes that smokers could satisfy their nicotine cravings with

For example, he said, we need to know what impact electronic cigarettes will have on a smoker compared with traditional methods to stop smoking, such as nicotine patches or gum, because those methods have not proved to be very successful

It does this by neutralizing the odour molecules