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Additionally, individuals who used e-cigarettes for longer than three years not only exhibit reduced microvascular function but also diminished macrovascular dysfunction, implying that those who use the product for a longer time are at risk of systemic vascular effects [128]

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These officials were bonded and were forbidden [32]under heavy penalties to pass bad tobacco, engage in the tobacco trade, or to take rewards

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Because the products are relatively new, their potential for harm is still under investigation, but early research suggests they could have long-term health consequences