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Description
It is mainly related to smoking

Increased Risk of Diseases Smoking increases the risk of various diseases such as lung cancer, heart disease, stroke and respiratory infections

more than 1 } : CS1 maint: DOI inactive as of July 2025 (link) Endocrine

Smoking reduction, smoking cessation, and incidence of fatal and non-fatal myocardial infarction in Denmark 19761998: a pooled cohort study

Physicians do not recommend heavy vaping
The trend prompted the World Health Organization to issue a statement in 2008 calling for more safety testing