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In 1895, George Augustus Sala commented in London Up to Date : An omnibus conductor, nowadays, would, I suppose, were the epithet of cad applied to him, resent the appellation as a scandalous insult

Profit, Wigand said

Doctors say there are several reasons marijuana might cause more lung damage than tobacco

Advertisement by the Metropolitan Life Insurance Company Newsweek February 4, 1957 Curators note: The following quote from 1954 is possibly the first mention by the Metropolitan Life Insurance Company of a relationship between cigarette smoking and heart disease: If your doctor finds that you have any form of heart trouble, he will tell you so