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These biases can be overcome by using family-based GWAS estimates and conducting standard MR methods [93, 94] or by specific within-family MR methods [95]

Strategies such as probiotics, prebiotics, and dietary modifications, which aim to restore microbial balance, could be explored as adjunct therapies to smoking cessation programs

all these play an important role in inhibiting natural conception. Dr Singh said that this makes natural conception more difficult and lowers the success rate of in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and other reproductive procedures, and added, it is also linked with decreased ovarian reserve and increased risk of miscarriage, thereby increasing the load on those already afflicted with infertility
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Screening ends after 15 years of cessation or if surgery is not feasible, with cessation support remaining the most effective way to reduce disease risk [83]

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