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Discovery of novel pyrazole derivatives as a potent anti-inflammatory agent in RAW264.7 cells via inhibition of NF-kB for possible benefit against SARS-CoV-2

10.1016/j.cbi.2008.05.003 3 Al-AskarM.BhatR

doi: 10.1016/j.scitotenv.2022.156890 33 JablouneR.KhalilM.Ben MoussaI

M., Park M

The formula works, but the result exposes a dosing problem

Notably, like proteasome inhibitors, high-dose AUR also transcriptionally induces ChaC1, the rate-limiting enzyme in glutathione (GSH) catabolism [27]
