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It should be noted that the Danish study included a smaller sample size ( n = 838,265) than ours ( n = 12,144,972, especially for rare outcomes, for example, the risk estimate for omphalocele in the Danish study was based on 25 exposed cases)

10.1016/0140-6736(92)93147-f [DOI] [PubMed] [Google Scholar] 100.EEA

ISSN 1072-4710

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These include studies of individuals with ADHD, in which the self-medication hypothesis suggests that substance use is a self-medication for attentional deficits