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Microglia display discordant complex I/complex IV ratios signaling NF-B-driven M1 polarization, while astrocytes shift toward glycolysis, exacerbating lactate accumulation and BBB compromise [50]

(2001) [86] reported that L-Carnitine, acting as a cofactor in fatty acid transport, may have a reparative effect by eliminating elevated intracellular levels of toxic acetyl-coenzyme A or by replacing fatty acids in the phospholipid membrane

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In contrast, fat-6 and fat-7 were not required for lifespan regulation in worms with ectopic SFP-1 expression (Fig

[DOI] [PubMed] [Google Scholar] Pillinger T, Mccutcheon RA, Vano L, et al