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For example, CAF cells activate the Wnt/-catenin pathway by increasing the expression of miR-92a-3p exosomes and inhibit mitochondrial cell death by directly suppressing F-Box and WD Repeat Domain Containing 7 (FBXW7) and modulator of apoptosis 1 (MOAP1), thereby promoting cell stemness and EMT in CRC (Hu et al., 2019)

After pretreatment, infection, or transfection, cell medium was exchanged for medium containing lethal compounds and 0.022 M of the viability dye SYTOX Green (SG, Cat