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This effect is exactly what makes these medications potentially dangerous for people with eating disorders

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doi:10.1016/S2213-8587(25)00027-0

doi: 10.1016/j.bbr.2015.07.024 144 CaiHYYangJTWangZJZhangJYangWWuMNet al

Indeed, acute elevated peripheral insulin levels may increase insulin in cerebrospinal fluid, whereas, chronic peripheral hyperinsulinemia (such as insulin resistance or T2DM) may downregulate insulin receptors of the BBB, impair brain insulin uptake, and ultimately lead to learning, memory, and cognitive deficits (52)