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It is especially important for energy and fat metabolism
- reducerea colesterolului

Defective or insufficient mitochondrial function at the cellular level is thought to impact whole-body metabolic homeostasis
In terms of mitochondrial dynamics, excessive androgens are responsible for the decreased mitochondrial fusion and increased fission-induced fragmentation, as evidenced by the marked increase in Drp1 gene expression in the liver of mice with PCOS (135)

The Journal of Physiology
