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Gene set enrichment analysis (GSEA) identified distinct biological processes enriched in the T-cell compartment of LC indicating sustained activation

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Therefore, in view of the controversy of the above studies, more high-quality double-blind RCTs are needed to further verify the effectiveness of vitamin E in preventing CIPN

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doi: 10.3390/md21080440

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Agents that conjugate to glutathione, such as APR-246, as well as chemical or genetic inhibition of glutathione biosynthesis, disrupt tumor cell growth and induce a ferroptosis-like form of cell death (Liu et al., 2017)

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