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As hard as its symptoms are to ignore, accurately diagnosing CHS can be tricky, physicians say, partly because those symptoms mimic other gastrointestinal conditions and because patients arent always straightforward about their habits

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This full-thickness loss of the epidermis results in a high death rate

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These findings support the hypothesis that the 3 subunit, expressed in the medial habenula of the brain, may regulate aversive or withdrawal-related effects of nicotine rather than its initial rewarding properties