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Many studies try to avoid including participants with comorbidities in things like substance use, and even psychiatric conditions like anxiety and depression, in order to avoid confounding results

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HONEY HOLLS: Experience the refreshing taste of a frosty winter day, with the warming aroma of sweet and tangy honey

Some focused on packaging, others on flavors

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this is a requirement to publish in the journal) So an action that is meant to reduce IRB burden (i.e., the NIHs definition of exemption categories) is not actually permitted to save much work, because I still have to submit a proposal to the IRB (albeit a shorter proposal) and they still have to review it, only for them to tell me what is already obvious (that my research is exempt)