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However, frequent vaping can raise blood nicotine levels to match or exceed those of smoking
[20] Randomized controlled trials have provided "high-certainty" evidence that e-cigarettes containing nicotine are more effective than nicotine replacement therapy for discontinuing tobacco smoking, and moderatecertainty evidence that they are more effective than e-cigarettes free of nicotine

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Upper Body Muscles (including Shoulders and Arms): Used more in running for balance and maintaining rhythm

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The 2011 research led by Segerstrm sa B from Department of Health Sciences, Lund University, Sweden, found that upper body muscle strength and endurance have a correlation with exercise capacity in cycling, as evidenced by improved maximal oxygen consumption (O2peak) and work rate (WRpeak) in sedentary healthy male subjects after six months of combined training, suggesting that upper body strength, particularly in the arms, chest, and trunk, can enhance cycling performance by enabling the rider to effectively transmit force from the handlebar to the pedals