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This group includes known cancer-causing chemicals, such as formaldehyde, and suspected carcinogens, such as acetaldehyde
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The pH of aerosol produced by the IQOS heated tobacco product and mainstream smoke produced from conventional cigarettes were found to be largely comparable (Salman et al., 2019) suggesting that a meaningful difference in the relative percentages of the various protonated forms of nicotine between the heated tobacco product and conventional cigarettes is unlikely

Lack of Regulation: The vaping industry has faced challenges with inadequate regulation and oversight, leading to concerns about product quality, safety standards, and accurate labelling