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In addition, the upper gum has fewer salivary glands nearby

The sensitivity analysis data for tolerant users are additionally shown in Figure 13 based on the ratio between no-tolerance and high tolerance dosage as shown in Table 2 27,37,42,43,44,45,46,47,48,49,50,51,52,53,54

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of products: 21 Moisture content (%) :8.201.40 Nicotine (mg/g product) :19.852.24 pH :10.410.24 Unprotonated nicotine (% of total) :99.480.18 NNN (g/g product) :1.910.35 Unprotonated nicotine (mg/g product) :16.9277.38 NNK (g/g product) :0.930.17 NNAL (g/g product) :0.260.08

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However, we aimed to avoid over-adjustment and multicollinearity by selecting a limited number of covariates that were both theoretically justified and available across the full time series