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But there is more: the continuance of smoking makes the brain respond to nicotine by increasing the number of nicotine receptors on the surface of its cells, an authentic snowball effect that invariably leads to dependency

(2009, June 22)
Coincidentally, just as I was moving away from home, the no smoking movement was gaining ground

Science 371 , 255260 (2021)

Its true, I dont like to talk about my work

If the drug is not reintroduced, the altered level of signaling will eventually induce the nerve cells to once again make compensatory changes that restore an appropriate balance of activities within the brain
