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Tell your doctor about all your other medicines, especially: valproic acid or divalproex sodium (Depakene or Depakote) a diuretic or "water pill"

The drugs initially were developed to treat diabetes, before their weight loss benefits were observed

Pharmacologic approaches to glycemic treatment: Standards of Medical Care in Diabetes2022 A

Food & Drug Administration (2021) FDA approves first generic of once-daily GLP-1 injection to lower blood sugar in patients with type 2 diabetes, U.S

Mitra MS, Lancaster K, Adedeji AO, Palanisamy GS, Dave RA, Zhong F, Holdren MS, Turley SJ, Liang WC, Wu Y, Meng YG, Vernes JM, Schutten MM

Abstract Alterations of endothelial function, inflammatory activation, and nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway are involved in the pathophysiology of heart failure