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More recently, TP53 missense mutations were identified in BCC samples, including hotspot positions p.H179Y, p.S241F, p.G245N, and p.R280K, clustering in p53 DBD [100]

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This subtype shows a unique gene expression signature involving human leucocyte antigens and many immune checkpoint regulators, including PD-L1 and CTLA-4

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Like other miRNAs, miR34c can inhibit the transcription or initiate the degradation of target gene mRNAs by binding to the 3UTR (89)

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