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and 6) continued tobacco use, despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by tobacco

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They include: people 45 years to 64 years old non-Hispanic American Indian or Alaska Native adults

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Vapour from vape devices usually contains nicotine, which has a similar risk profile to coffee, but with fewer harmful elements than tobacco smoke

The cancer risk associated with alcohol is worse for women because for moderate levels of consumption, for example one bottle of wine per week, the alcohol-associated cancer risk is higher for breast cancer than other cancers related to drinking